Use of indocyanine green and the HyperEye system for detecting sentinel lymph nodes in breast cancer within a population of European patients: a pilot study.
Oldřich CoufalVuk FaitPublished in: World journal of surgical oncology (2016)
The study did not confirm the hypothesis that the use of ICG with the HyperEye system can currently be considered a method fully comparable with using RI and a gamma probe in a population of European patients. Although the detection rate is high, a significantly lower number of SLNs were detected using ICG than using RI (p = 0.03). Thus, there would be a higher probability for false negatives to occur in using SLN biopsy. This is caused mainly by the limited permeability of tissues to fluorescent radiation and the difficulty therefore of detecting nodes located deeper beneath the body's surface.
Keyphrases
- end stage renal disease
- ejection fraction
- lymph node
- chronic kidney disease
- newly diagnosed
- gene expression
- prognostic factors
- squamous cell carcinoma
- peritoneal dialysis
- sentinel lymph node
- early stage
- patient reported outcomes
- radiation therapy
- photodynamic therapy
- fluorescence imaging
- patient reported
- radiation induced
- sensitive detection
- fluorescent probe
- fine needle aspiration