Riociguat can ameliorate bronchopulmonary dysplasia in the SU5416 induced rat experimental model.

Shinichi KatsuragiHidekazu IshidaHidehiro SuginobeHirofumi TsuruRenjie WangChika YoshiharaAtsuko UeyamaJun NaritaRyo IshiiShigetoyo KogakiKeiichi Ozono

Published in: Experimental lung research (2021)

Riociguat could ameliorate pulmonary alveolarization, vascularization, and hypertension in the SU5416 induced BPD rat model, but could not improve the overall survival.

Keyphrases

pulmonary hypertension
high glucose
diabetic rats
blood pressure
oxidative stress
drug induced
endothelial cells
free survival
stress induced