A cross-sectional observational study to assess socio-demographic factors in newly diagnosed TB DM comorbidity.
Rashmi HullalliM R GudadinniRohith MotappaPublished in: F1000Research (2022)
Background: Tuberculosis (TB) and diabetes mellitus (DM) co-morbidity is one of the rising public health problems. There is growing evidence that DM is an important risk factor for TB. This study was carried out to know the prevalence of DM among newly detected sputum positive pulmonary TB patients registered in District Tuberculosis Centre and to assess the risk factors of DM among TB patients. Methods: In a cross-sectional study, newly detected sputum positive pulmonary TB patients were screened for DM (those having symptoms of DM). Furthermore, they were diagnosed by detecting blood glucose levels (≥200 mg/dL). Mean, standard deviation (SD), Chi-squared and Fisher-Freeman-Halton exact tests were used to determine the significant associations. P-values less than 0.05 were considered to be statistically significant. Results: A total of 215 TB patients were included in this study. The prevalence of DM among TB patients was found to be 23.7% (2.8% known and 97.8% new cases). Significant associations were found between age (>46 years old), educational status, smoking habits, alcohol consumption, physical activity, presence of DM symptoms and family history of DM. Conclusions: Routine screening for DM is mandatory due to its increasing prevalence, which may help in early diagnosis and to reduce complications by proper management that in turn helps in the successful outcome of TB treatment.
Keyphrases
- metabolic syndrome
- newly diagnosed
- mycobacterium tuberculosis
- end stage renal disease
- risk factors
- public health
- chronic kidney disease
- blood glucose
- peritoneal dialysis
- glycemic control
- emergency department
- adipose tissue
- alcohol consumption
- type diabetes
- blood pressure
- south africa
- body mass index
- hepatitis c virus
- pulmonary tuberculosis
- human immunodeficiency virus
- density functional theory
- hiv aids