Respective roles of Glycoprotein VI and FcγRIIA in the regulation of αIIbβ3-mediated platelet activation to fibrinogen, thrombus buildup, and stability.

Muhammad Usman AhmedNicolas ReceveurEmily Janus-BellClarisse MouriauxChristian GachetMartine Jandrot PerrusBéatrice HechlerElizabeth E Gardiner Pierre H Mangin

Published in: Research and practice in thrombosis and haemostasis (2021)

This study provides evidence that GPVI, but not FcγRIIA, induces platelet activation and spreading on fibrinogen, and promotes thrombus buildup and stability.

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