The Clinical and Psychosocial Outcomes for Women Who Received Unexpected Clinically Actionable Germline Information Identified through Research: An Exploratory Sequential Mixed-Methods Comparative Study.
Laura Elenor ForrestRowan Forbes ShepherdErin TuttyAngela PearceIan G CampbellLisa DevereuxAlison H TrainerPaul A JamesMary-Anne YoungPublished in: Journal of personalized medicine (2022)
There were no adverse psychological outcomes amongst women who received clinically actionable germline information through a model of 'genome-first' care compared to those who did not. These findings support the return of clinically actionable research results to research participants.
Keyphrases
- polycystic ovary syndrome
- dna repair
- healthcare
- pregnancy outcomes
- palliative care
- health information
- cervical cancer screening
- quality improvement
- breast cancer risk
- type diabetes
- gene expression
- clinical trial
- genome wide
- social media
- insulin resistance
- dna methylation
- metabolic syndrome
- adipose tissue
- sleep quality
- depressive symptoms