Altered Brainstem Pain-Modulation Circuitry Connectivity During Spontaneous Pain Intensity Fluctuations.

Emily P MillsZeynab AlshelhDanny KosanovicFlavia Di PietroE Russell VickersPaul M MaceyLuke A Henderson

Published in: Journal of pain research (2020)

These data reveal that moment-to-moment changes in brainstem pain-modulation circuitry functioning likely contribute to fluctuations in spontaneous pain intensity in individuals with chronic neuropathic pain.

Keyphrases

neuropathic pain
chronic pain
spinal cord
spinal cord injury
pain management
high intensity
gene expression
dna methylation
machine learning
genome wide
electronic health record
big data