Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging.
Nicolò GennaroAndrea MarrariSalvatore Lorenzo RenneFerdinando Carlo Maria CananziVittorio Lorenzo QuagliuoloLucia Di BrinaMarta ScorsettiGiovanna PepeArturo ChitiArmando SantoroLuca BalzariniLetterio Salvatore PolitiAlexia Francesca BertuzziPublished in: The British journal of radiology (2020)
Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Besides CT and MRI, hybrid imaging including positron emission tomography (PET)/CT and PET/MRI are giving an increasing contribution to provide functional insights about tumour biology and to improve the diagnostic accuracy of the imaging work-up. This review paper provides a revision of the pathology, clinical and radiological features of adult RMS, with a particular focus on the growing role of hybrid PET-based imaging.
Keyphrases
- pet ct
- positron emission tomography
- computed tomography
- high resolution
- magnetic resonance imaging
- contrast enhanced
- emergency department
- ejection fraction
- total knee arthroplasty
- lymph node
- magnetic resonance
- young adults
- diffusion weighted imaging
- prognostic factors
- patient reported
- image quality
- dual energy
- fine needle aspiration