TXNIP hypomethylation and its interaction with obesity and hypertriglyceridemia increase type 2 diabetes mellitus risk: A nested case-control study.

Dongdong ZhangCheng ChengMeng CaoTieqiang WangXiaoliang ChenYang ZhaoBingyuan WangYongcheng RenDechen LiuLeilei LiuXu ChenFeiyan LiuQionggui ZhouGang TianQuanman LiChunmei GuoHonghui LiJian WangRuirong ChengYongcheng RenMing Zhang

Published in: Journal of diabetes (2020)

TXNIP methylation is associated with T2DM incidence in a Chinese population. Interaction between TXNIP methylation and environmental factors may influence T2DM risk and needs more investigation.

Keyphrases

nlrp inflammasome
glycemic control
dna methylation
metabolic syndrome
genome wide
type diabetes
insulin resistance
weight loss
risk factors
weight gain
skeletal muscle
cardiovascular risk factors