SCA Medium: A New Culture Medium for the Isolation of All Candida auris Clades.
Ahmad IbrahimLucie PeyclitRim AbdallahSaber KhelaifiaAmanda ChamiehJean-Marc RolainFadi BittarPublished in: Journal of fungi (Basel, Switzerland) (2021)
Candida auris is an emerging multidrug-resistant yeast causing nosocomial infections and associated with high mortality in immunocompromised patients. Rapid identification and characterisation are necessary for diagnosis and containing its spread. In this study, we present a selective culture medium for all C. auris clades. This medium is sensitive with a limit of detection ranging between 101 and 102 CFU/mL. The 100% specificity of SCA (specific C. auris) medium is confirmed on a set of 135 Candida strains, 50 bacterial species and 200 human stool samples. Thus, this medium specifically selects for C. auris isolation from clinical samples, allowing the latter to study its phenotypic profile.
Keyphrases
- multidrug resistant
- candida albicans
- end stage renal disease
- chronic kidney disease
- endothelial cells
- loop mediated isothermal amplification
- type diabetes
- prognostic factors
- cardiovascular disease
- peritoneal dialysis
- risk factors
- staphylococcus aureus
- coronary artery disease
- pseudomonas aeruginosa
- patient reported
- induced pluripotent stem cells
- bioinformatics analysis