Long acting aripiprazole influences cognitive functions in recent onset schizophrenia.
Vjekoslav PeitlMario ŠtefanovićIvona OrlovićJelena CulejAna RendulićKrunoslav MatešićDalibor KarlovićPublished in: Psychopharmacology (2021)
Our findings suggest that aripiprazole LAI improves individual cognitive functions in recent onset schizophrenia. Investigated COMT polymorphism (Met/Met genotype), as well as the COMT-MTHFR interaction, were positively associated with attention and executive functioning (perseveration), potentially implying COMT's biomarker potential in terms of cognition in schizophrenia.