Blocking Periostin Prevented Development of Inflammation in Rhabdomyolysis-Induced Acute Kidney Injury Mice Model.

Jun MuratsuFumihiro SanadaNobutaka KoibuchiKana ShibataNaruto KatsuragiShoji IkebeYasuo TsunetoshiHiromi RakugiRyuichi MorishitaYoshiaki Taniyama

Published in: Cells (2022)

POSTN was highly expressed in the kidney through rhabdomyolysis and was a positive regulator of AKI. Targeting POSTN might propose a new therapeutic strategy against the development of acute renal failure.

Keyphrases

acute kidney injury
cardiac surgery
drug induced
oxidative stress
liver failure
transcription factor
high glucose
type diabetes
respiratory failure
cancer therapy
high fat diet induced
intensive care unit
hepatitis b virus
aortic dissection
stress induced
endothelial cells
wild type
mechanical ventilation