TNFSF4 is a risk factor to systemic lupus erythematosus in a Latin American population.
Mario Adán Moreno-EutimioCarmen Estefanía Martínez-AlemánIvan Sammir Aranda-UribeGuillermo Aquino-JarquinCarlos Cabello-GutierrezJosé Manuel FragosoRosa Elda Barbosa-CobosMiguel A SaavedraJulián Ramírez BelloPublished in: Clinical rheumatology (2020)
Our results show that TNFSF4 rs1234315T/C, rs2205960G/T, and rs704840T/G are risk factors to SLE in Mexicans. This is the first study to document an association between TNFSF4 rs704840T/G and SLE in a Latin American population. In addition, our meta-analysis showed that TNFSF4 rs2205960G/T is a risk factor for Asians and Latin Americans. Key Point • The TNFSF4 rs1234315T/C, rs2205960G/T, and rs704849T/G SNVs are risk factors to SLE in patients from Mexico.