A synthetic pregnenolone analog promotes microtubule dynamics and neural development.
Viktoryia KolasJose Sandino A BandonilNiaz WaliKuo-Chiang HsiaJiun-Jie ShieBon-Chu ChungPublished in: Cell & bioscience (2022)
We have developed compound #43, a nonmetabolized P5 analog, that recapitulates P5 functions in vivo and can be a new therapeutic candidate for the treatment of neurodevelopmental diseases.