Association between serum 25-hydroxyvitamin D and global DNA methylation in visceral adipose tissue from colorectal cancer patients.

Daniel Castellano-CastilloSonsoles MorcilloAna B CrujeirasLidia Sánchez-AlcoholadoMercedes Clemente-PostigoEsperanza TorresFrancisco José TinahonesManuel Macias-González

Published in: BMC cancer (2019)

We showed for the first time an association between LINE-1 DNA methylation in VAT and vitamin D levels in subjects with colorectal cancer, highlighting the importance of VAT from cancer patients, which could be modified epigenetically compared to healthy subjects.

Keyphrases

dna methylation
adipose tissue
gene expression
genome wide
ejection fraction
insulin resistance
newly diagnosed
prognostic factors
metabolic syndrome
long noncoding rna
patient reported