A PD-1 high CD4 + T Cell Population With a Cytotoxic Phenotype is Associated With Interstitial Lung Disease in Systemic Sclerosis.
Mehreen ElaheeAlisa A MuellerRunci WangKathryne E MarksTakanori SasakiYe CaoAndrea FavaPaul F DellaripaFrancesco BoinDeepak A RaoPublished in: ACR open rheumatology (2024)
cells with cytotoxic features is specifically expanded in patients with SSc and is significantly associated with interstitial lung disease severity. This potential cytotoxicity appearing in the CD4 T cell population can be evaluated as a prognostic disease biomarker in patients with SSc.