Sestrin2 and Beclin1 levels in Polycystic Ovary Syndrome.
Vahid SaeediMona NourbakhshMitra NourbakhshLadan HaghighiLeila KamalzadehSamira Ezzati MobasserMaryam Razzaghy-AzarPublished in: Journal of clinical laboratory analysis (2021)
Our findings highlight the dysregulation of sestrin2 as a marker of autophagy in PCOS and its potential usefulness as a novel biomarker for PCOS. Further research is needed to better understand the role of this protein in the pathophysiology of PCOS and its value as a diagnostic tool for the evaluation of PCOS patients.
Keyphrases
- polycystic ovary syndrome
- insulin resistance
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- cell death
- prognostic factors
- oxidative stress
- signaling pathway
- peritoneal dialysis
- metabolic syndrome
- type diabetes
- endoplasmic reticulum stress
- small molecule
- binding protein
- amino acid
- protein protein