Differential impact of PI3K/AKT/mTOR signaling on tumor initiation and progression in animal models of prostate cancer.
Shuaibin WangChao ZhangZhifang XuMichael H ChenHaiyan YuLizhong WangRunhua LiuPublished in: The Prostate (2022)
Our results for genetically engineered mouse models suggest a differential role of the PI3K/AKT/mTOR signaling nodes in prostate cancer initiation and progression, but the underlying molecular mechanisms remain unaddressed.