Differential impact of PI3K/AKT/mTOR signaling on tumor initiation and progression in animal models of prostate cancer.

Shuaibin WangChao ZhangZhifang XuMichael H ChenHaiyan YuLizhong Wang Runhua Liu

Published in: The Prostate (2022)

Our results for genetically engineered mouse models suggest a differential role of the PI3K/AKT/mTOR signaling nodes in prostate cancer initiation and progression, but the underlying molecular mechanisms remain unaddressed.

Keyphrases

prostate cancer
radical prostatectomy

mouse model
sentinel lymph node

radiation therapy
neoadjuvant chemotherapy

rectal cancer