Safety of Combined Statin and Fibrate Therapy: Risks of Liver Injury and Acute Kidney Injury in a Cohort Study from the Shizuoka Kokuho Database.
Yohei SobukawaTaichi HattaDaito FunakiEiji NakataniPublished in: Drugs - real world outcomes (2024)
We have demonstrated higher risks of 1-year hospitalization with liver injury or acute kidney injury associated with the use of combinations of statins and fibrates. This underscores the need for a cautious approach to the prescribing of such drug combinations and the importance of monitoring patients for potential adverse events.
Keyphrases
- liver injury
- drug induced
- adverse drug
- acute kidney injury
- end stage renal disease
- human health
- cardiovascular disease
- primary care
- chronic kidney disease
- ejection fraction
- newly diagnosed
- cardiac surgery
- peritoneal dialysis
- risk assessment
- coronary artery disease
- emergency department
- type diabetes
- stem cells
- patient reported outcomes
- climate change
- cell therapy
- patient reported