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Variable cellular decision-making behavior in a constant synthetic network topology.

Najaf A ShahCasim A Sarkar
Published in: BMC bioinformatics (2019)
Our study illustrates how parameters that do not change the topological structure of a decision-making network can nonetheless exert significant influence on its response dynamics. These findings should further inform the study of native motifs, including the effects of topology-preserving mutations, and the robust engineering of synthetic networks.
Keyphrases
  • decision making