Development of novel and non-invasive diagnostic markers for lower urinary tract symptoms using urothelial cells in voided urine.

Hiroshi ShimuraTakahiko MitsuiSachiko TsuchiyaTatsuya MiyamotoTatsuya IharaSatoru Kira Hiroshi NakagomiNorifumi SawadaYuki ImaiTakanori MochizukiMasayuki Takeda

Published in: Neurourology and urodynamics (2017)

The expressions of Cxs and TRP channels on urothelial cells in voided urine could be related to LUTS. Further analysis of urothelial cells in voided urine has the potential to reveal the mechanism of the LUTS and develop new markers with non-invasive methods.

Keyphrases

lower urinary tract symptoms
induced apoptosis
benign prostatic hyperplasia
cell cycle arrest
high grade
endoplasmic reticulum stress
signaling pathway
gene expression
risk assessment
cell proliferation
dna methylation
single cell