Association of obesity under different metabolic status with adverse outcomes in patients with chronic myeloid leukemia: A retrospective cohort study.

Yingchun DongYiping ChengXiaoshan FengZinuo YuanHang DongYue ZhangJunming HanYafei WuZhixiang WangXia ZhongXiude Fan Jiajun Zhao

Published in: Journal of diabetes (2023)

Metabolic abnormalities were associated with adverse outcomes in patients with CML, irrespective of obesity status. Future treatment of patients with CML should consider the effects of obesity on their adverse outcomes under different metabolic status, especially in female patients.

Keyphrases

chronic myeloid leukemia
insulin resistance
weight loss
metabolic syndrome
high fat diet induced
type diabetes
weight gain
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
skeletal muscle
prognostic factors
adipose tissue
patient reported outcomes
current status
replacement therapy