Foreskin surface area is not associated with sub-preputial microbiome composition or penile cytokines.
Godfrey KigoziCindy M LiuDaniel E ParkZoe R PackmanRonald H GrayRupert KaulAaron A R TobianAlison G AbrahamJoseph SsekasanvuJoseph KagaayiJessica L ProdgerPublished in: PloS one (2020)
Larger foreskin size is not associated with either increased penile anaerobes or pro-inflammatory cytokines. These data suggest that foreskin size does not increase HIV-1 risk through changes in penile microbiome composition or penile inflammation.