Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases.

Heini M L KallioReija HietaLeena LatonenAnniina BrofeldtMatti AnnalaKati KivinummiTeuvo L TammelaMatti NykterWilliam B IsaacsHans G LiljaG Steven BovaTapio Visakorpi

Published in: British journal of cancer (2018)

AR-V3, AR-V7 and AR-V9 are co-expressed in CRPC metastases highlighting the fact that inhibiting AR function via regions common to all AR-Vs is likely to provide additional benefit to patients with CRPC.

Keyphrases

gene expression
copy number