Modulation of Gr1low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice.

S BéliardWilfried Le GoffF Saint-CharlesL PoupelV DeswaerteL BouchareychasThierry HubyP Lesnik

Published in: International journal of obesity (2005) (2017)

By using transgenic female mice and adoptive transfer experiments, we established the evidence for a correlation between Gr1low monocyte subset and weight gain and RT. Hence, this specific Gr1low monocyte subset could be used as a target for acting on AT inflammation and RT.

Keyphrases

weight gain
high fat diet
body mass index
birth weight
dendritic cells
insulin resistance
endothelial cells
adipose tissue
weight loss
high fat diet induced
oxidative stress
peripheral blood
type diabetes
cell therapy
physical activity
gestational age
bone marrow
preterm birth