β-Eudesmol Inhibits the Migration of Cholangiocarcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT and p38MAPK Modulation.

Bishwanath AcharyaWanna ChajaroenkulKesara Na-Bangchang

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

Altogether, the anti-metastatic activity of β-eudesmol might be due to its suppressive effect on EMT via modulating the PI3K/AKT and p38MAPK signaling cascades.

Keyphrases

signaling pathway
epithelial mesenchymal transition
pi k akt
cell cycle arrest
induced apoptosis
transforming growth factor
cell death
squamous cell carcinoma
small cell lung cancer
cell proliferation