Severe Acute Kidney Injury in Cardiovascular Surgery: Thrombotic Microangiopathy as a Differential Diagnosis to Ischemia Reperfusion Injury. A Retrospective Study.
Melissa GrigorescuChristine-Elena KamlaDietmar WassilowskyDominik JoskowiakSven PeterßStephan KemmnerMaximilian PichlmaierChristian HaglMichael FischerederUlf SchönermarckPublished in: Journal of clinical medicine (2020)
Our findings suggest TMA as an important differential diagnosis of severe AKI following cardiovascular surgery, which may be triggered by aortic surgery. Therefore, early diagnosis and timely treatment of TMA could reduce kidney damage and improve mortality of AKI following cardiovascular surgery, which should be further investigated.
Keyphrases
- minimally invasive
- coronary artery bypass
- ischemia reperfusion injury
- surgical site infection
- acute kidney injury
- oxidative stress
- early onset
- aortic valve
- coronary artery disease
- cardiovascular disease
- percutaneous coronary intervention
- heart failure
- cardiovascular events
- left ventricular
- risk factors
- acute coronary syndrome
- pulmonary hypertension
- coronary artery
- single molecule
- smoking cessation