Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesis.

Ramya RamaswamiTakanobu TagawaGuruswamy MaheshAnna SerquinaVishal KopardeKathryn LurainSarah DremelXiaofan LiAmeera MungaleAlex BeranZoe Weaver OhlerLaura BasselAndrew WarnerRalph MangusanAnaida WidellIrene EkwedeLaurie T KrugThomas S UldrickRobert YarchoanJoseph M Ziegelbauer

Published in: Journal of translational medicine (2023)

This study of transcriptional profiling of KS tissue provides novel insights into the characteristics and pathogenesis of this unique virus-driven neoplasm.

Keyphrases

gene expression
genome wide
transcription factor
single cell
endothelial cells
heat shock
low grade
vascular endothelial growth factor
dna methylation
oxidative stress