Carbon monoxide polyhemoglobin improves the therapeutic effect and relieves inflammation in the colon tissue of haemorrhagic shock/resuscitation rats.

Shasha HaoHuan WangShen LiHonghui ZhangXintong XieJiaxin LiuChengmin YangWentao Zhou Hong Wang

Published in: Artificial cells, nanomedicine, and biotechnology (2024)

In these haemorrhagic shock/resuscitation models, both polyCOHb and polyHb show similar therapeutic effects, and polyCOHb has more effective effects in maintaining MAP, correcting acidosis, reducing inflammatory responses than that in polyHb.

Keyphrases

cardiac arrest
oxidative stress
cardiopulmonary resuscitation
septic shock