Specific microRNA/mRNA expression profiles and novel immune regulation mechanisms are induced in THP-1 macrophages by in vitro exposure to Trichosporon asahii.

Mingwang ZhangZhikuan XiaXin YangJunhong AoRongya Yang

Published in: Mycoses (2021)

This study evaluated the expression profiles of miRNA/mRNA and revealed the immunological consequences of THP-1 macrophages in response to T. asahii exposure. Moreover, our data suggest that miR-342-3p can indirectly promote inflammatory responses and may be a potential therapeutic target against trichosporonosis.

Keyphrases

high glucose
electronic health record
single cell
drug induced
risk assessment
oxidative stress
binding protein
human health
climate change