Tregs dysfunction aggravates postoperative cognitive impairment in aged mice.

Yile ZhouHuihui JuYan HuTingting LiZhouyi ChenYuan SiXia SunYi ShiHao Fang

Published in: Journal of neuroinflammation (2023)

Blocking peripheral regulatory T cells improves surgery-induced cognitive function in aged mice. Therefore, aged Tregs play an essential role in the occurrence of POCD.

Keyphrases

regulatory t cells
cognitive impairment
high fat diet induced
dendritic cells
minimally invasive
patients undergoing
oxidative stress
high glucose
diabetic rats
coronary artery bypass
insulin resistance
adipose tissue
metabolic syndrome
immune response