Ventricular volume expansion in presymptomatic genetic frontotemporal dementia.
Tamara P TavaresDerek G V MitchellKristy ColemanChristen ShoesmithRobert BarthaDavid M CashKatrina M MooreJohn van SwietenBarbara BorroniDaniela GalimbertiMaria Carmela TartagliaJames RoweCaroline GraffFabrizio TagliaviniGiovanni FrisoniStefano CappaRobert Jr LaforceAlexandre de MendonçaSandro SorbiGarrick WallstromMario MasellisJonathan D RohrerElizabeth C Fingernull nullPublished in: Neurology (2019)
Ventricular volume differences are detectable in presymptomatic genetic FTD. Concordance of results from time-intensive manual editing and fully automatic segmentation approaches support its value as a measure of disease onset and progression in future studies in both presymptomatic and symptomatic genetic FTD.