The effect of HIV infection on glycaemia and renal function in type 2 diabetic patients.
Siyabonga P KhozaNigel John CrowtherSindeep BhanaPublished in: PloS one (2018)
These data suggest that glycaemic control is worse in type 2 diabetic subjects with HIV infection and that HbA1c underestimates glycaemia in these patients. Albuminuria was not associated with HIV-positivity. The negative relationship of CD4 counts with glucose levels may reflect viral removal and easing of the associated inflammatory response. It is possible that the association of statin and anti-hypertensive therapies with high HbA1c and glucose levels, respectively, is due to such therapies being given largely to subjects with poor glycaemic control.
Keyphrases
- antiretroviral therapy
- inflammatory response
- type diabetes
- end stage renal disease
- hiv infected
- human immunodeficiency virus
- newly diagnosed
- hiv positive
- ejection fraction
- chronic kidney disease
- blood pressure
- prognostic factors
- hiv aids
- sars cov
- blood glucose
- hepatitis c virus
- cardiovascular disease
- coronary artery disease
- peritoneal dialysis
- immune response
- electronic health record
- skeletal muscle
- metabolic syndrome
- lipopolysaccharide induced
- lps induced
- peripheral blood
- toll like receptor
- deep learning
- data analysis
- weight loss
- low density lipoprotein