Acute toxicity of craniospinal irradiation with volumetric-modulated arc therapy in children with solid tumors.
Kenneth K WongOmar RagabHung N TranAnthony PhamSean AllJonathan WaxerArthur J OlchPublished in: Pediatric blood & cancer (2018)
VMAT CSI, along with chemotherapy and anesthesia, is feasible with supportive care. Daily image-guided RT improves accuracy and reduces the risk of spinal cord overdose without increasing treatment time. Further research is needed to determine whether reducing doses to organs, such as thyroid, heart, or hippocampus, offsets the risk of increased volume of low-dose irradiation.
Keyphrases
- low dose
- spinal cord
- healthcare
- liver failure
- palliative care
- heart failure
- young adults
- respiratory failure
- high dose
- physical activity
- oxidative stress
- spinal cord injury
- locally advanced
- radiation induced
- quality improvement
- aortic dissection
- atrial fibrillation
- pain management
- mesenchymal stem cells
- drug induced
- brain injury
- affordable care act
- extracorporeal membrane oxygenation
- blood brain barrier
- cell therapy
- subarachnoid hemorrhage
- acute respiratory distress syndrome