Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice.

Baocai WangBenedikt KaufmannCarolin MoglerSuyang ZhongYuhan YinZhangjun ChengRoland M SchmidHelmut FriessNorbert HüserGuido von FiguraDaniel Hartmann

Published in: PloS one (2023)

Brg1 promotes the progression of liver fibrosis in mice and may therefore be used as a potential therapeutic target for treating patients with liver fibrosis due to chronic injury.

Keyphrases

liver fibrosis
high fat diet induced
oxidative stress
high glucose
diabetic rats
drug induced
type diabetes
insulin resistance
endothelial cells