Levothyroxine and the risk of adverse pregnancy outcomes in women with subclinical hypothyroidism: a systematic review and meta-analysis.

Magnus BeinOriana Hoi Yun YuSonia Marzia GrandiFrancesca Y E FratiIhab KandilKristian B Filion

Published in: BMC endocrine disorders (2021)

Treatment of SCH with levothyroxine during pregnancy is associated with decreased risks of pregnancy loss and neonatal death. Given the paucity of available data and heterogeneity of included studies, additional studies are needed to address the benefits of levothyroxine use among pregnant women with SCH.

Keyphrases

pregnancy outcomes
pregnant women
case control
single cell
electronic health record
replacement therapy
big data
emergency department
preterm birth
machine learning
combination therapy
risk assessment
adverse drug
climate change