Association of PTPN22 polymorphism and its correlation with Graves' disease susceptibility in Polish adult population-A preliminary study.

Natalia Wawrusiewicz-KurylonekOlga Martyna Koper-LenkiewiczJoanna GościkJanusz MyśliwiecPrzemysław PawłowskiAdam Jacek Krętowski

Published in: Molecular genetics & genomic medicine (2019)

Our preliminary study suggest that PTPN22:c.1858C>T gene polymorphism may be associated with a predisposition to GD within the adult north-eastern Polish population. The studied polymorphism of the PTPN22 gene did not significantly affect the risk of ophthalmopathy developing and disease manifestation before the age of 40.

Keyphrases

south africa
genome wide
gene expression
dna methylation
tertiary care
young adults
childhood cancer
solid state