Effect of IL-15 addition on asbestos-induced suppression of human cytotoxic T lymphocyte induction.
Naoko Kumagai-TakeiYasumitsu NishimuraHidenori MatsuzakiSuni LeeKei YoshitomeTatsuo ItoTakemi OtsukiPublished in: Environmental health and preventive medicine (2021)
These findings indicate that CTLs induced upon exposure to asbestos possess dysfunctional machinery that can be partly compensated by IL-15 supplementation, and that IL-15 is more effective in the recovery of proliferation and granzyme B levels from asbestos-induced suppression of CTL induction compared with IL-2.