Ethical preparedness of data monitoring committees (DMCs) to oversee international clinical trials: a qualitative descriptive study.
Alex Nginyo HingaAkram IbrahimDiego VintimillaMickayla JonesLisa EcksteinAnnette RidSeema K ShahDorcas KamuyaPublished in: BMJ global health (2024)
This study is one of the first to consider the ethical implications of DMC structure, membership and deliberations. The potential overuse of DMCs, DMC member recruitment processes that seem somewhat insular, limited training for DMC members, and divergent approaches to deliberation may limit the capacity of DMCs for addressing ethical issues. Further research on DMC structure and processes could help enhance the ethical preparedness of DMCs.