Tissue and Serum Biomarkers in Degenerative Aortic Stenosis-Insights into Pathogenesis, Prevention and Therapy.
Alkistis KapelouzouStyliani A GeronikolouIrene LidorikiChristos KontogiannisLoukas KaklamanisLoukas TsourelisDennis V CokkinosPublished in: Biology (2023)
We showed that six widely prevalent biomarkers affecting the atherosclerotic process were also involved in DAS, suggesting a strong osteogenic and pro-inflammatory profile, indicating that aortic valve calcification is a multifactorial biological process.
Keyphrases
- aortic valve
- aortic stenosis
- transcatheter aortic valve replacement
- aortic valve replacement
- transcatheter aortic valve implantation
- ejection fraction
- left ventricular
- mesenchymal stem cells
- bone marrow
- disease activity
- systemic lupus erythematosus
- heart failure
- rheumatoid arthritis
- cell therapy
- atrial fibrillation