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EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy.

Lindsay CanhamSam SendacMannekomba R DiagbougaElena WolodimeroffDaniela PirriBlanca Tardajos AyllonShuang FengCeline SouilholTimothy J A ChicoPaul C EvansJovana Serbanovic-Canic
Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)
We identified EVA1A as a novel flow-sensitive gene that mediates the effects of proatherogenic DF on EC dysfunction by regulating autophagy.
Keyphrases
  • oxidative stress
  • endoplasmic reticulum stress
  • cell death
  • cell cycle arrest
  • signaling pathway
  • endothelial cells
  • genome wide
  • copy number
  • cell proliferation