Adipolin/C1q/Tnf-related protein 12 prevents adverse cardiac remodeling after myocardial infarction.
Tomonobu TakikawaKoji OhashiHayato OgawaNaoya OtakaHiroshi KawanishiLixin FangYuta OzakiShunsuke EguchiMinako TatsumiMikito TakefujiToyoaki MuroharaNoriyuki OuchiPublished in: PloS one (2020)
Our data indicate that adipolin ameliorates pathological remodeling of myocardium after MI, at least in part, by its ability to reduce myocardial inflammatory response and apoptosis.
Keyphrases
- inflammatory response
- left ventricular
- oxidative stress
- mouse model
- rheumatoid arthritis
- endoplasmic reticulum stress
- lipopolysaccharide induced
- cell cycle arrest
- electronic health record
- cell death
- lps induced
- big data
- emergency department
- machine learning
- immune response
- signaling pathway
- atrial fibrillation
- drug induced