Topical application of Chinese herbal medicine DAEP relieves the osteoarthritic knee pain in rats.
Wing Sum SiuWai Ting ShumWen ChengChun Wai WongHoi Ting ShiuChun Hay KoPing Chung LeungChristopher Wai Kei LamChun-Kwok WongPublished in: Chinese medicine (2019)
DAEP exhibited its effect via the nuclear factor (NF)-κB pathway by suppressing the phosphorylation of IκB kinase αβ (p-IKKαβ) and cyclooxygenase-2 (COX-2) protein expression. This study provides scientific evidence to support the clinical application of the Chinese herbal paste on reliving OA pain.