Medial amygdalar tau is associated with anxiety symptoms in preclinical Alzheimer's disease.

Joyce S LiSamantha M TunBronte Ficek-TaniWanwan XuSelena WangCorey L HorienTakuya ToyonagaShreya S NuliCaroline J ZeissAlbert R PowersYize ZhaoElizabeth C MorminoCarolyn A Fredericks

Published in: bioRxiv : the preprint server for biology (2024)

Our findings suggest that preclinical tau deposition in the amygdala may result in meaningful changes in functional connectivity which may predispose patients to mood symptoms.

Keyphrases

functional connectivity
resting state
sleep quality
end stage renal disease
ejection fraction
newly diagnosed
cerebrospinal fluid
peritoneal dialysis
cell therapy
prognostic factors
bipolar disorder
cognitive decline
depressive symptoms
mild cognitive impairment