Scutellarin protects the kidney from ischemia/reperfusion injury by targeting Nrf2.

Jie DaiChenyu LiLong ZhaoChen GuanChengyu YangNingxin ZhangBin ZhouYue ZhangLin WangWei JiangCongjuan LuoYan Xu

Published in: Nephrology (Carlton, Vic.) (2022)

Scu led to up-regulation of HO-1 through activating the Nrf2 signalling pathway, protecting the kidneys from ischemia/reperfusion (I/R)-induced oxidative damage.

Keyphrases

oxidative stress
ischemia reperfusion injury
diabetic rats
high glucose
signaling pathway
pi k akt
cell proliferation