Evaluation of the Robustness of Therapeutic Drug Monitoring Coupled with Bayesian Forecasting of Busulfan with Regard to Inaccurate Documentation.
Adrin DadkhahDzenefa AlihodzicAstrid BroekerNicolaus KrögerClaudia LangebrakeSebastian G WichaPublished in: Pharmaceutical research (2021)
The estimated AUC was not affected substantially by inaccurate documentation of sampling and infusion time. The calculated rPEs and rRmses of estimated AUC indicate robustness and reliability for TDM of busulfan, even in presence of erroneous records.