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Evaluation of the Robustness of Therapeutic Drug Monitoring Coupled with Bayesian Forecasting of Busulfan with Regard to Inaccurate Documentation.

Adrin DadkhahDzenefa AlihodzicAstrid BroekerNicolaus KrögerClaudia LangebrakeSebastian G Wicha
Published in: Pharmaceutical research (2021)
The estimated AUC was not affected substantially by inaccurate documentation of sampling and infusion time. The calculated rPEs and rRmses of estimated AUC indicate robustness and reliability for TDM of busulfan, even in presence of erroneous records.
Keyphrases
  • electronic health record
  • advance care planning
  • allogeneic hematopoietic stem cell transplantation
  • low dose
  • acute lymphoblastic leukemia