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GSH-resistant and highly cytoselective ruthenium(II)-p-cymene-(imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenol complexes as potential anticancer agents.

Binoy KarUtpal DasSourav DeSudhindra PeteAjay Sharma SNilmadhab RoyAshok Kumar S KDebashis PandaPriyankar Paira
Published in: Dalton transactions (Cambridge, England : 2003) (2021)
To avoid the side effects of the current popular platinum-based anticancer drugs, researchers have made tireless attempts to design appropriate GSH-resistant Ru(ii)-arene complexes. In this regard, luminescent ruthenium(ii)-p-cymene-imidazophenanthroline complexes were developed as promising highly cytoselective cancer theraputic agents for HeLa and Caco-2 cells.
Keyphrases
  • cell cycle arrest
  • induced apoptosis
  • fluorescent probe
  • papillary thyroid
  • quantum dots
  • cell death
  • oxidative stress
  • human health
  • squamous cell
  • water soluble
  • childhood cancer
  • drug induced
  • lymph node metastasis