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Mutational variant allele frequency profile as a biomarker of response to immune checkpoint blockade in non-small cell lung Cancer.

Ruyun GaoNing LouLin LiTongji XiePuyuan XingLe TangJiarui YaoXiaohong HanYuan-Kai Shi
Published in: Journal of translational medicine (2024)
The mutational VAF profile is a promising biomarker for ICI therapy in NSCLC, with enhanced therapeutic stratification and management as a supplement to PD-L1 or TMB.
Keyphrases
  • small cell lung cancer
  • advanced non small cell lung cancer
  • bone marrow