Safety of intrathecal route: focus to methylprednisolone acetate (Depo-Medrol) use.

Joel SchlatterDavid NguyenMichèle ZamySofiane KabicheJean-Eudes FontanSalvatore Cisternino

Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2017)

Intrathecal methylprednisolone acetate (Depo-Medrol) therapy seems not fully safe due to reported adverse events. The use of other forms of corticosteroid therapy free from excipients should be emphasized such as soluble methylprednisolone sodium succinate.

Keyphrases

high dose
low dose
stem cells
mesenchymal stem cells
smoking cessation