Intraduodenal infusion of a combination of tastants decreases food intake in humans.
Mark van AvesaatFreddy J TroostDina RipkenJelmer PetersHenk Fj HendriksAdrian A M MascleePublished in: The American journal of clinical nutrition (2015)
Intraduodenal infusion of umami and a combination of tastants inhibits feelings of hunger, but only the latter also reduces food intake. However, these alterations were not accompanied by changes in the plasma concentrations of the gut-derived peptides cholecystokinin, GLP-1, or PYY. This trial was registered at clinicaltrials.gov as NCT01956838.