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Significant Advancement in Various Synthetic Strategies and Pharmacotherapy of Piperine Derivatives: A Review.

Sagar JoshiSalahuddin SalahuddinDr Avijit MazumderRajnish KumarKm ShabanaSonakshi TyagiKavita RanaMohamed Jawed AhsanMohammad Shahar YarArvind AryaNavneet Khurana
Published in: Current topics in medicinal chemistry (2023)
This review article provides a thorough examination of piperine and the source plant. The best extraction technique for the extraction of piperine and the synthesis of its analogs with various biological activities, including antihypertensive, antidiabetic, insecticidal, antibacterial, and antibiotic properties, are covered in the article. This review aims to provide an updated analysis of the literature on the synthesis of piperine analogs.
Keyphrases
  • systematic review
  • molecular docking
  • blood pressure
  • smoking cessation
  • silver nanoparticles
  • hypertensive patients
  • cell wall
  • molecular dynamics simulations
  • structure activity relationship